Nanomaterials have emerged as smart agents with growth-promoting and stress-emulating potential for sustainable agriculture. In recent years, biopolymers have shown great potential as plant growth stimulants. In this study, chitosan, alginate and BSA have been used to prepare CS-Alg-BSA NPs as nanopriming agent for wheat seeds. The prepared samples remodeled biochemical attributes in primed seeds and improved the germination parameters. The priming-treatments significantly increased the vital biomolecules including proteins and sugars. It controlled ROS production, up-regulated antioxidants and significantly reduced MDA. These biochemical readjustments consequently improved the final germination percentage, germination energy and germination index. The priming memory imprints enabled the seeds to show sustainable germination and uniform seedling development for climate-smart growth.