Over the years, the European Cohesion Policy has undergone significant transformation. The targeting mechanisms and programming strategies have been continuously adapted and redefined to respond effectively to the evolving developmental challenges of EU regions. 

During the 2014-2020 programming period a “place-based approach” emerged. In the current programming period the policy seems to be in its "mature" era characterized by integrated approaches and relevant financial mechanisms. We are no longer talking about regional inequalities’ recovery, emphasis is on comparative advantages of areas to boost their growth potential and build on its unique characteristics. 

Using the “core-periphery” approach, this paper argues that small municipalities should change their developmental trajectory with synergies and interconnection that foster collaboration rather than competition. This model may assist the disadvantaged areas to overcome structural disadvantages. Through the theoretical lens of the core-periphery model, is examined how the networking of disadvantaged areas can rescale growth potential and create multiplicative benefits. Such approaches require the empowerment of small municipalities to pursue integrated planning, find technical competence and ensure the political commitment to the partnership. Recent reforms in Greek legislation further support these efforts (such as Law 4674/2020) and provide new pathways for integrated sustainable development.

Using Didymoticho as a case study, this paper builds the theoretical assumption that remote or/and disadvantaged areas can benefit from integrated development plans and collaborative structures that enable holistic interventions and improve access to funding.