Considering the present global fuel scenario, it becomes highly inevitable to opt for biofuel. Yet the use of biodiesel had increased pollutants which are emitted to the atmosphere such as Carbon monoxide, Unburnt Hydrocarbon, Nitrogen oxides and Smoke density in the combustion products. For this analysis, a novel and naturally obtainable antioxidant (Coffea Arabica antioxidant) has been experimented. With POME20 (20% palm oil Methyl ester and 80% diesel fuel), a proportion yielding favorable results based on several studies, Coffea Arabica antioxidant additive was infused in different proportions (ppm’s) to obtain the test blends. The thus derived blends PSBC500, PSBC1000, PSBC1500 and PSBC2000 in addition to plain DF and POME20 were used in diesel engine that is of the type, single cylinder DI water cooled TV-1 Kirloskar, under different load conditions. The test results showed improved BSFC and BTE for Coffea Arabica antioxidant infused blends. The atmospheric pollutants emitted from the engine such as CO, UHBC, NOx and SD were reduced considerably for the antioxidant additive infused POME20 blends simultaneously not creating any adverse impact in the performance of the engine. Among the test blends, PSBC 2000 was found performing with the closer tolerating characters as the plain diesel fuel.